Will my arthritis medications interact with other medications?
Yes, arthritis medications could interact with other medications. For example methotrexate. It is an immunosuppressive medication. Folic acid, one of the B vitamins, is often given to clients who are taking methotrexate to help decrease some of the drug’s side effects. Another is, you should avoid co-administering methotrexate and Nexium (esomeprazole) for it may increase the serum concentration of methotrexate. Hence, consulting your doctor regarding your arthritis medications is a must to understand more about this.
Methotrexate must not be administered together with tetracyclines and other drugs such as NSAIDs, penicillins, salicylates, and sulfonamides for they interact with each other. Methotrexate blood levels and toxicity may increase which is very dangerous for the client. Hence you have to be careful and know how arthritis medications affect your med intake.
When methotrexate is co-administered with charcoal, its efficacy may be reduced. When administered together with Digoxin, its level may be reduced and its actions altered/ reduced. To understand more about your arthritis medications, consult your doctor.
Hydantoins administered together with methotrexate can reduce the plasma levels. Hence, arthritis medications must be well administered too. Trimethoprim when co-administered with methotrexate may increase the risk of megaloblastic anemia and bone marrow suppression. You don’t want to get worse the interaction of your arthritis medications to other medications.
Oral antibiotics such as chloramphenicol must not be administered together with methotrexate for its intestinal absorption may reduce or it may interfere with enterohepatic circulation (the circulation of substances like bile salts that are absorbed in the intestine and are carried to the liver wherein they will be secreted into the bile and again enter the intestine). Hence you see the vital interaction of your arthritis medications to other medications.
For safety purposes and well being of the client, discuss everything with your physician first before taking anything that will react with your arthritis medications.
Prednisone, a glucocorticoid, interacts with calcium/ vitamin D. It may impair the absorption of prednisone. But it contributes a minor effect only. You must be well versed with your arthritis medications to avoid any interactions with other medications. A particular intervention is not needed for this though clinicians must be aware of the potential for reaction. Well, awareness of your arthritis medications would prevent you to any unlikely interaction with other medications.
For patients taking Lasix (Furosemide), they should be closely monitored for when taken with Prednisone, hypokalemia may occur. If it happens then potassium supplements must be provided to compensate for the electrolyte imbalance. Hence, arhtritis medications must be monitored too.
Prednisone interacts with anticholinesterases. It antagonizes the effect in myasthenia gravis. It interacts with anticoagulants too. The dose requirement is altered. Hence, arthritis medications interacts with other medications. In theophyllines, both drugs’ efficacy may be altered. For salicylates, its serum levels and efficacy may be reduced. Wit cyclosporine, the toxicity may be increased. Arthritis medications must be taken seriously and its interaction with any medications.
For safety purposes, again it is best to consult with your physician and discuss with him your arthritis medications.
Gold interacts with antimalarials and penicillamine. Their safety is unknown. Therefore precautionary measures must be taken before taking these drugs together. And of course, knowing your arthritis medications with the interactions with these drugs is important. Gold interacts with immunosuppressives as well. It may increase the risk of blood dyscrasias (pathologic conditions such as leukemia or hemophilia). Hence, consulting a doctor about your arthritis medications is very very necessary.
Before taking gold sodium thiomalate, inform your physician first about every drug you take be it prescription drugs or OTC (over the counter) drugs as well as your vitamins, minerals and herbal medicines so that your safety is ensured and you are closely monitored. Hence, arthritis medications must also be monitored.